SUPR-3D: A randomized phase iii trial comparing simple unplanned palliative radiotherapy versus 3d conformal radiotherapy for patients with bone metastases: study protocol

Table 2 Follow-up schedule

	Pre-Treatment		Treatment		Follow-Up		Early Termination
Tests & Procedures	Recruitment	Enrollment/ Baseline	Day 1	Day 5	Week 2 Day 14 (+/− 3 days)	Week 4 Day 28 (+/− 3 days)	(collect only if patient allows/agrees)
Pre-Screen	X
Informed Consent	X
Eligibility Screen		X
^aHistory and physical exam		X
^aPregnancy Test (if applicable)		X
Patient Diary (provided to patient)			X	X Day 1–5
^b Brief Pain Inventory		X	X		X	X	X
Functional Living Index - Emesis		X	X		X	X	X
PRO-CTCAE & QoL EORTC QLQ-C15-PAL			X		X	X	X
Treatment Related Data			X
HCP-reported baseline and follow up form (Medications and Toxicity)		X			X	X	X

^a may be done within 90 days, or 3 months, prior to enrollment
^b BPI on Day 1 does not need to be administered again if collection was done within 1 week of baseline

ISSN: 1471-2407