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Table 1 Suggested constraints

From: SUPR-3D: A randomized phase iii trial comparing simple unplanned palliative radiotherapy versus 3d conformal radiotherapy for patients with bone metastases: study protocol

 

8 Gy in 1 fraction

20 Gy in 5 fractions

aSpinal Cord

Max dose < 110% of 8 Gy

Max dose < 110% of 20 Gy

Lungs (excl. GTV)

V6 Gy < 35%

V12 Gy < 35%

Mean dose < 6 Gy

Mean dose < 12 Gy

Kidney (each)

V6 Gy < 30%

V12 < 30%

 

Mean dose < 5 Gy

Mean dose < 10 Gy

bSmall Bowel

Max dose < 110% of 8 Gy

Max dose < 110% of 20 Gy

  1. a spinal cord to L2, spinal cord PRV is 0.5 cm margin around the spinal cord
  2. b small bowel contoured by RO or RT depending on institutional polices