Fig. 3
From: Exploring new potential role of DDB2 by host cell reactivation assay in human tumorigenic cells
The loss of DDB2-PCNA interaction determines defects in NER pathway. HeLa cells transiently transfected with pc-DNA3.1-DDB2Wt or pc-DNA3.1-DDB2PCNA- constructs and UV-C local irradiated were analysed 30 min and 1 h after damage. In a representative co-localization analysis between DDB2 and Polymerase II proteins after UV-induced damages as obtained by confocal microscopy. The co-localization analyses are reported in panel (b). Data are at least from three independent experiments