Table 3 Univariate analysis of factors for overall survival in patients with early stage pancreatic cancer, Kaplan-Meier method
Factors | No. of patients (%) | Median OS [95% CI] | P value |
|---|---|---|---|
Sex | .11 | ||
Male | 32 (65.3%) | 12.0 [4.4–19.6] | |
Female | 17 (34.7%) | 22.0 [10.1–33.9] | |
Age | .47 | ||
75≥, and < 80 | 38 (77.6%) | 16.0 [10.0–22.0] | |
≥ 80 | 11 (22.4%) | 10.0 [5.5–14.5] | |
BMI | .57 | ||
< 25 | 43 (87.8%) | 13.0 [7.5–18.5] | |
≥ 25 | 6 (12.2%) | 19.0 [9.4–28.6] | |
Smoking | .32 | ||
Yes | 14 (29.8%) | 13.0 [5.2–20.8] | |
No | 33 (70.2%) | 16.0 [10.2–21.8] | |
Alcohol | .33 | ||
Yes | 16 (34%) | 12.0 [0.3–23.8] | |
No | 31 (66%) | 16.0 [10.7–21.3] | |
HTN | .74 | ||
Yes | 24 (50%) | 12.0 [6.0–18.0] | |
No | 24 (50%) | 17.0 [6.1–27.9] | |
DM | .58 | ||
Yes | 22 (45.8%) | 9.0 [5.2–12.8] | |
No | 26 (54.2%) | 10.9–23.1] | |
Charlson comorbidity Index | .04 | ||
0 | 21 (42.9%) | 19.0 [12.5–25.5] | |
1 | 18 (36.7%) | 9.0 [0.7–17.3] | |
2 | 7 (14.3%) | 16.0 [5.7–26.3] | |
3 | 3 (6.1%) | 6.0 [4.4–7.6] | |
ECOG | .18 | ||
0 | 11 (22.4%) | 22.0 [12.6–31.4] | |
1 | 32 (65.3%) | 14.0 [7.3–20.7] | |
2 | 4 (8.2%) | 5.0 [2.1–7.9] | |
3 | 2 (4.1%) | 6.0 | |
Family hx. of malignancy | .27 | ||
Yes | 7 (14.3%) | 9.0 [6.4–11.6] | |
No | 42 (85.7%) | 16.0 [8.5–23.5] | |
Location of tumor | .84 | ||
Head | 12.0 [6.3–17.7] | ||
Body & Tail | 19.0 [2.6–35.4] | ||
Hb (g/dL) | .59 | ||
≥ 13 | 19 (38.8%) | 16.0 [6.2–25.8] | |
< 13 | 30 (61.2%) | 13.0 [2.5–23.5] | |
PT (INR) | .10 | ||
≤ 1.2 | 43 (93.5%) | 16.0 [8.6–23.4] | |
> 1.2 | 3 (6.5%) | 9.0 [4.2–13.8] | |
T. Bil | .92 | ||
≤ 1.2 | 32 (65.3%) | 16.0 [6.3–25.7] | |
> 1.2 | 17 (34.7%) | 14.0 [10.2–17.9] | |
Albumin (g/dL) | .55 | ||
≥ 3.3 | 45 (91.8%) | 16.0 [10.8–21.2] | |
< 3.3 | 4 (8.2%) | 12.0 [0.0–24.0] | |
CA 19–9 (U/mL) | .38 | ||
≤ 37 | 14 (29.2%) | 10.0 [8.3–11.8] | |
> 37 | 34 (70.8%) | 16.0 [10.4–21.6] | |
Stage | .12 | ||
1 | 5 (10.2%) | 22.5 [15.0–30.0] | |
2 | 44 (89.8%) | 13.0 [7.5–18.5] | |
Surgical resection | .02 | ||
Yes | 38 (77.6%) | 16.0 [5.1–26.9] | |
No | 11 (22.4%) | 10.0 [4.6–15.4] | |
CTx. and/or RTx. | .09 | ||
Yes | 17 (34.7%) | 22.0 [8.6–35.4] | |
No | 32 (65.3%) | 10.0 [4.6–15.4] |