Fig. 4

a~c The expression of TNF-α, IL-6, IL-8 in Arr2+ mice and control with different dosage of paclitaxel treatment was assessed with real-time PCR, and was measured by 2-ΔΔCT(** P < 0.01). For all three factors, P = 0.000 between each treatment group for both control and Arr2+ mice except those between 20 mg and 10 mg (P = 0.050), and between 10 mg and 0 mg (P = 0.051) in control for the measurement of IL-6