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Table 1 Patient Characteristics

From: Efficacy, safety and feasibility of fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric patients receiving moderately and highly emetogenic chemotherapy – results of a non-interventional observation study

Patient Characteristics

Fosaprepitant group

Control group

p-value

N = 40

N = 39

n (%)

n (%)

Age

 < 2 years

5 (12.5)

5 (12.8)

0.7676

 2–6 years

11 (27.5)

14 (35.9)

0.5752

 7–12 years

11 (27.5)

8 (20.5)

0.6432

 13–17 years

13 (32.5)

12 (30.8)

0.939

Sex

 Male

25 (62.5)

22 (56.4)

0.7474

 Female

15 (37.5)

17 (43.6)

 

Diagnosis

 ALL

10 (25.0)

8 (20.5)

0.8359

 AML

0 (0.0)

1 (2.6)

0.4937

 ALL relapse

2 (5.0)

2 (5.1)

> 0.9999

 Astrocytoma

1 (2.5)

1 (2.6)

> 0.9999

 Non-Hodgkin Lymphoma

4 (10.0)

5 (12.8)

0.737

 Ependymoma

1 (2.5)

1 (2.6)

> 0.9999

 Ewing’s sarcoma

4 (10.0)

4 (10.3)

> 0.9999

 Germinoma

1 (2.5)

1 (2.6)

> 0.9999

 Hepatoblastoma

3 (7.5)

2 (5.1)

> 0.9999

 Hodgkin’s Lymphoma

2 (5.0)

1 (2.6)

> 0.9999

 Medulloblastoma

2 (5.0)

1 (2.6)

> 0.9999

 MDS

1 (2.5)

0 (0.0)

> 0.9999

 Nephroblastoma

0 (0.0)

1 (2.6)

0.4937

 Neuroblastoma

3 (7.5)

3 (7.7)

> 0.9999

 Osteosarcoma

1 (2.5)

2 (5.1)

> 0.9999

 Renal cell carcinoma

0 (0.0)

1 (2.6)

0.4937

 Rhabdomyosarcoma

4 (10.0)

2 (5.1)

0.6752

 T cell lymphoma

1 (2.5)

3 (7.7)

0.3589

  1. A statistically significant difference of the patient characteristics between the two groups could not be detected (p > 0.05; Chi-square test with Yate’s correction or Fisher’s exact test)
  2. Abbreviations: ALL acute lymphoblastic leukemia, AML acute myeloid leukemia, N total number of patients per cohort, n sample size, MDS myelodysplastic syndromes