|
Group
|
SMAD4 expression
|
χ2
|
p-value
|
|---|
|
Intact SMAD4
|
Lost SMAD4
|
|---|
|
Sex
|
|
Male
|
8 (34.78%)
|
25 (34.7%)
|
<0.001
|
1.000
|
|
Female
|
15 (65.22%)
|
47 (65.3)
| | |
|
Age (year)
|
|
<60
|
11 (47.8%)
|
19 (26.4%)
|
3.708
|
0.072
|
|
≥60
|
12 (52.2%)
|
53 (73.6%)
| | |
|
Tumor diameter (cm)
|
|
<3
|
11 (47.8%)
|
15 (20.8%)
|
6.389
|
0.016
|
|
≥3
|
12 (52.2%)
|
57 (79.2%)
| | |
|
TNM tumor staging
|
|
IA~IIA
|
21 (91.3%)
|
46 (63.9%)
|
6.303
|
0.016
|
|
IIB~IV
|
2 (8.7%)
|
26 (36.1%)
| | |
|
Lymphatic invasion
|
|
Yes
|
2 (8.7%)
|
70 (97.2%)
|
74.451
|
<0.001
|
|
No
|
21 (91.3%)
|
2 (2.8%)
| | |
|
Tumor location
|
|
Head
|
11 (47.8%)
|
47 (65.3%)
|
2.233
|
0.149
|
|
Body and tail
|
12 (52.2%)
|
25 (34.7%)
| | |
|
Differentiation
|
|
High and middle differentiation
|
12 (52.2%)
|
19 (26.4%)
|
5.272
|
0.039
|
|
Poorly differeftiation
|
11 (47.8%)
|
53 (73.6%)
| | |
|
Perineural invasion
|
|
Yes
|
9 (39.1%)
|
22 (30.6%)
|
0.583
|
0.610
|
|
No
|
14 (60.9%)
|
50 (69.4%)
| | |
- The bold values indicate P values less than 0.05
