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Table 2 Differentially expressed tissue miRNAs across clinical parameters as measured by sequencing and microarray

From: Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients

Comparison

miRNA

Fold change sequencing

Adjusted P-value sequencing

Fold change microarray

Adjusted P-value microarray

Transplantation vs Resection in Tumor Tissue

 

hsa-miR-107

−0.902

0.041

−0.317

0.844

hsa-miR-17-5p

−1.179

0.041

−0.439

0.844

hsa-miR-339-5p

−1.255

0.041

NA

NA

hsa-miR-505-3p

−1.077

0.042

−0.170

0.966

hsa-miR-20a-5p

−1.150

0.043

−0.364

0.844

hsa-miR-532-3p

−1.276

0.043

−1.157

0.841

hsa-miR-1248

−1.847

0.049

NA

NA

hsa-miR-93-5p

−0.949

0.049

−0.168

0.941

Transplantation vs Resection in Normal Tissue

 

hsa-miR-224-5p

1.328

0.005

0.689

0.584

hsa-miR-451a

−1.977

0.005

0.205

0.817

hsa-miR-193b-3p

−1.202

0.011

0.367

0.539

hsa-miR-19b-3p

−0.972

0.015

−0.114

0.821

hsa-miR-16-5p

−0.989

0.015

−0.023

0.951

hsa-miR-543

1.451

0.028

NA

NA

hsa-miR-345-5p

−0.767

0.028

NA

NA

hsa-miR-324-5p

−1.354

0.028

0.581

0.410

hsa-miR-101-5p

−1.298

0.030

NA

NA

hsa-miR-17-3p

−0.922

0.030

0.412

0.582

hsa-miR-675-3p

−1.374

0.032

NA

NA

hsa-miR-485-3p

1.206

0.032

NA

NA

hsa-miR-128-3p

1.087

0.032

0.504

0.535

hsa-miR-195-3p

0.887

0.032

NA

NA

hsa-miR-146b-5p

0.710

0.038

0.420

0.572

hsa-miR-15b-3p

−1.170

0.038

NA

NA

hsa-miR-652-3p

−1.019

0.038

0.664

0.503

hsa-miR-660-3p

−1.126

0.047

NA

NA

Cirrhosis vs Non-Cirrhosis in Normal Tissue

 

hsa-miR-146b-5p

1.027

0.003

1.128

0.031

Cirrhosis vs Non-Cirrhosis in Tumor Tissue

 

hsa-miR-141-3p

−2.886

0.003

NA

NA

  1. “Comparison” shows the clinical parameters between which the comparison was performed; “miRNA” shows the miRBase miRNA name; “Fold Change Sequencing” shows the log2 fold change value for the miRNA in the sequencing data; “Adjusted P-value Sequencing” shows the Benjamini-Hochberg asdjusted p-value in the sequencing data. “Fold Change Microarray” shows the log2 fold change value for the miRNA in the microarray data; “Adjusted P-value Microarray” shows the Benjamini-Hochberg asdjusted p-value in the microarray data. “NA” indicates that the miRNA is not detected. Positive fold change indicates upregulation in transplantation or cirrhosis for the two comparisons