Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients

BMC Cancer

Table 1 Differentially expressed serum miRNA across clinical parameters

Comparison	miRNA	Fold change	Average expression	Adjusted P-value
Transplantation vs Resection
	hsa-miR-651-5p	1.690	2.692	0.003
	hsa-miR-6511b-3p	−2.107	2.524	0.005
	hsa-miR-197-3p	−1.888	6.484	0.007
	hsa-miR-92b-3p	−1.571	8.678	0.018
	hsa-miR-374a-3p	1.801	3.822	0.022
	hsa-miR-6511a-3p	−2.094	2.999	0.022
	hsa-miR-7706	−1.036	5.388	0.022
	hsa-miR-362-3p	1.457	1.880	0.023
	hsa-miR-483-3p	−2.412	2.966	0.026
	hsa-miR-3605-3p	−1.487	5.241	0.034
	hsa-miR-125a-5p	−1.962	8.930	0.042
	hsa-miR-425-5p	−0.972	10.199	0.046
	hsa-miR-450b-5p	1.554	6.006	0.046
	hsa-miR-205-5p	−2.338	2.917	0.046
	hsa-miR-6741-3p	−1.978	1.678	0.046
	hsa-miR-378c	1.312	6.059	0.046
	hsa-miR-550a-3p	−1.893	4.457	0.046
HBV vs Non-HBV
	hsa-miR-122-3p	2.929	2.364	8.45E-05
	hsa-miR-194-5p	1.470	7.536	0.007

“Comparison” shows the clinical parameters between which the comparison was performed; “miRNA” shows the miRBase miRNA name; “Fold Change” shows the log2 fold change value for the miRNA; “Average Expression” shows the average expression (cpm, log2) of the miRNA across samples; “Adjusted P-value” shows the Benjamini-Hochberg asdjusted p-value. Positive fold change indicates upregulation in transplantation or HBV for the two comparisons respectively

ISSN: 1471-2407