Table 1 Definition of endpoints
Endpoint | Event | Censoring | |||||||
|---|---|---|---|---|---|---|---|---|---|
Death from any cause | Local recurrence | Satellite metastasis | in-transit metastasis | Regional LN metastasis | Distant LN metastasis | Distant organ metastasis | Amputation for any cause | ||
Major relapse-free survival | + | – | + | + | + | + | + | – | Last day the patient is alive |
Local relapse-free survival | + | + | – | – | – | – | – | – | |
Digit-preservation survival | + | – | – | – | – | – | – | + | |
Relapse-free survival | + | + | + | + | + | + | + | – | |
Overall survival | + | – | – | – | – | – | – | – | |
Partial relapse-free survival | + | – | – | + | + | + | + | – | |