Table 5 DCE-MRI parameters with VS-GR/GRASP stratified according to TRGs and response
Parameters | TRG1–5 | responder and non-responder | ||
|---|---|---|---|---|
VS-GR | GRASP | VS-GR | GRASP | |
r*(P) | r* (P) | r* (P) | r* (P) | |
Ktrans max | 0.409 (0.001) | 0.343 (0.006) | 0.443(< 0.001) | 0.396 (0.001) |
Ktrans mean | 0.305 (0.014) | 0.320 (0.010) | 0.338 (0.006) | 0.307 (0.014) |
Ktrans 75% | 0.318 (0.011) | 0.282 (0.024) | 0.338 (0.006) | 0.279 (0.026) |
Kep max | 0.379 (0.002) | 0.323 (0.009) | 0.343 (0.006) | 0.381 (0.002) |
Kep mean | 0.314 (0.012) | 0.255 (0.042) | 0.215 (0.088) | 0.274 (0.029) |
Kep 75% | 0.283 (0.023) | 0.238 (0.058) | 0.179 (0.157) | 0.223 (0.077) |
Ve max | 0.097 (0.446) | −0.035 (0.784) | 0.208 (0.099) | −0.003 (0.979) |
Ve mean | 0.125 (0.324) | 0.318 (0.010) | 0.256 (0.041) | 0.335 (0.007) |
Ve 75% | 0.151 (0.234) | 0.330 (0.008) | 0.286 (0.022) | 0.307 (0.014) |
Vp max | 0.312 (0.012) | 0.333 (0.007) | 0.391 (0.001) | 0.412 (0.001) |
Vp mean | 0.158 (0.213) | 0.371 (0.003) | 0.228 (0.070) | 0.402 (0.001) |
Vp 75% | 0.115 (0.366) | 0.370 (0.003) | 0.210 (0.096) | 0.407 (0.001) |
AUC max | 0.524(< 0.001) | 0.253 (0.044) | 0.471(< 0.001) | 0.494(< 0.001) |
AUC mean | 0.294 (0.018) | 0.306 (0.014) | 0.343 (0.006) | 0.419 (0.001) |
AUC 75% | 0.314 (0.012) | 0.307 (0.014) | 0.353 (0.004) | 0.432(< 0.001) |