Table 4 Multivariate analyses compared with patients’ clinicopathological parameters, GSTs and HER2 status for bladder cancer overall survival

Group age (≤60/> 60 Years)

0.81

− 0.144

0.564

0.215

1.64

− 0.035

0.480

0.087

Gender (F/M)

2.77

−0.519

0.206

0.356

1.45

−0.137

0.398

0.319

Tumor grade (High/Low)

0.46

−0.558

0.167

0.255

0.52

−0.433

0.113

0.232

Tumor subtypes (Transitional/Squamous)

1.75

−0.383

0.363

0.953

1.41

−0.173

0.367

0.459

Tumor shape (nonpapillary/papillary)

1.48

−0.099

0.594

0.142

1.07

−0.207

0.335

0.626

Lymph node (present/absent)

1.88

−0.655

0.015

0.059

0.98

−0.581

−0.093

0.009

Vascular invasion (present/absent)

–

–

–

–

0.66

−0.496

0.026

0.075

Metastasis (present/absent)

0.36

−0.530

0.205

0.345

1.72

−0.496

0.033

0.083

Smoking (yes/no)

1.41

−0.914

0.839

0.788

0.94

−0.638

0.284

0.380

Family history of cancer (yes/no)

–

–

–

–

0.38

−0.578

0.338

0.546

GSTM1 status (present/null)

1.21

−0.400

0.374

0.940

0.95

−0.510

0.002

0.052

GSTP1 status (AA/AG + GG)

0.55

−0.422

0.350

0.837

0.71

−0.035

0.549

0.081

HER2 gene status (non-amplified/amplified)

2.38

−0.457

0.297

0.642

0.54

−0.214

0.345

0.627

HER2 protein status (no expression/expression)

2.14

−0.459

0.310

0.669

1.04

−0.151

0.390

0.366