Table 3 Univariate and multivariate analysis of predictive factors of impaired disease-free survival
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Gender | 0.79 | |||
Male | 1 | |||
Female | 1.2 (0.32–4,45) | |||
Histologic differentiation | 0.007 | 0.02 | ||
Well differentiated | 1 | 1 | ||
Poorly differentiated | 10.75 (1.90–58.67) | 9.23 (1.36–62.82) | ||
Pretherapeutic T stage | 0.94 | |||
T1-T2 | 1 | |||
T3-T4 | 0.94 (0.17–5.17) | |||
Pretherapeutic N stage | 0.66 | |||
N0 | 1 | |||
N1 | 0.68 (0.12–3.72) | |||
Neoadjuvant treatment | 0.66 | |||
radiotherapy alone | 1 | |||
Chemoradiotherapy | 0.61 (0.07–5.43) | |||
Surgical procedure | 0.89 | |||
APR | 1 | |||
Conservative intervention | 1.1 (0.29–4.10) | |||
Perineal sepsis | 0.005 | 0.008 | ||
No | 1 | 1 | ||
Yes | 7.32 (1.81–29.50) | 13.51(1.96–93.12) | ||