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Table 3 Univariate and multivariate analysis of predictive factors of impaired disease-free survival

From: Predictive factors of disease-free survival after complete pathological response to neoadjuvant radiotherapy for rectal adenocarcinoma: retrospective case series

  Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Gender   0.79   
Male 1    
Female 1.2 (0.32–4,45)    
Histologic differentiation   0.007   0.02
Well differentiated 1   1  
Poorly differentiated 10.75 (1.90–58.67)   9.23 (1.36–62.82)  
Pretherapeutic T stage   0.94   
T1-T2 1    
T3-T4 0.94 (0.17–5.17)    
Pretherapeutic N stage   0.66   
N0 1    
N1 0.68 (0.12–3.72)    
Neoadjuvant treatment   0.66   
radiotherapy alone 1    
Chemoradiotherapy 0.61 (0.07–5.43)    
Surgical procedure   0.89   
APR 1    
Conservative intervention 1.1 (0.29–4.10)    
Perineal sepsis   0.005   0.008
No 1   1  
Yes 7.32 (1.81–29.50)   13.51(1.96–93.12)