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Table 3 Characteristics of the patients with breast cancer

From: Atypical femoral fracture in patients with bone metastasis receiving denosumab therapy: a retrospective study and systematic review

  Number of patients
Characteristics n = 159 (%)
Stage at diagnosis
 I 17 (11)
 II 50 (31)
 III 32 (20)
 IV 31 (20)
 Unknown 28 (17)
Subtype
 HR+ HER2- 108 (68)
 HR+ HER2+ 20 (13)
 HR- HER2+ 9 (6)
 HR- HER2- 14 (9)
 Unknown 8 (5)
Perioperative chemotherapy
 Yes 61 (38)
 Anthracycline regimen 11 (7)
 Anthracycline + taxane regimen 26 (16)
 Other regimens 24 (15)
 No 97 (61)
 Unknown 1 (1)
Adjuvant endocrine therapy
 Aromatase inhibitor 39 (25)
 Tamoxifen 29 (19)
 Ovarian function suppression 22 (14)
 None 22 (14)
 Unknown 1 (1)
Prior treatment with zoledronic acid
 Yes 39 (25)
 No 92 (60)
 Unknown 23 (15)
Number of denosumab doses median 18 (range: 1–79)
More than 45 doses of denosumab 15 (9)
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