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Table 3 Characteristics of the patients with breast cancer

From: Atypical femoral fracture in patients with bone metastasis receiving denosumab therapy: a retrospective study and systematic review

 

Number of patients

Characteristics

n = 159 (%)

Stage at diagnosis

 I

17 (11)

 II

50 (31)

 III

32 (20)

 IV

31 (20)

 Unknown

28 (17)

Subtype

 HR+ HER2-

108 (68)

 HR+ HER2+

20 (13)

 HR- HER2+

9 (6)

 HR- HER2-

14 (9)

 Unknown

8 (5)

Perioperative chemotherapy

 Yes

61 (38)

 Anthracycline regimen

11 (7)

 Anthracycline + taxane regimen

26 (16)

 Other regimens

24 (15)

 No

97 (61)

 Unknown

1 (1)

Adjuvant endocrine therapy

 Aromatase inhibitor

39 (25)

 Tamoxifen

29 (19)

 Ovarian function suppression

22 (14)

 None

22 (14)

 Unknown

1 (1)

Prior treatment with zoledronic acid

 Yes

39 (25)

 No

92 (60)

 Unknown

23 (15)

Number of denosumab doses

median 18 (range: 1–79)

More than 45 doses of denosumab

15 (9)