Table 1 Dose and schedule of Capecitabine and Ziv-aflibercept
Cohort | # Evaluable Subjects | Capecitabine P.O. (mg/m2) BID, Days 1–14 | Ziv-Aflibercept I.V. (mg/kg) Q3 weeks, Day 1 |
|---|---|---|---|
Phase Ib (dose escalation) | |||
 Cohort 1 | 7 | 850 | 6 |
 Cohort 2 | 6 | 1000 | 6 |
Phase II (expansion) | 50 | 850 | 6 |