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Table 1 Baseline Patient and Tumor Characteristics

From: Incidence and risk factors for acute kidney injury in head and neck cancer patients treated with concurrent chemoradiation with high-dose cisplatin

Characteristic

Total (N = 124)

AKI (n = 85)

Non-AKI (n = 39)

Median age, (range), years

60 (30–74)

60 (30–71)

59 (41–74)

Male

97 (78)

67 (79)

30 (77)

ECOG performance status

 0

41 (33)

26 (31)

15 (38)

 1

76 (61)

55 (65)

21 (54)

 2

6 (5)

3 (4)

3 (8)

 Not specified

1 (1)

1 (1)

 Hypertension

25 (20)

20 (24)

5 (13)

 Diabetes mellitus

9 (7)

7 (8)

2 (5)

 Cognitive impairment

8 (6)

4 (5)

4 (10)

CCI

 0–1

92 (74)

61 (72)

31 (79)

 2–3

32 (26)

24 (28)

8 (21)

Smoking

  ≥ 10 pack-years

92 (74)

65 (76)

27 (69)

Alcohol

  ≥ 14 Units/week

46 (37)

35 (41)

11 (28)

 Number of nephrotoxic co-medications, median (range)

2 (0–3)

2 (0–3)

2 (1–3)

 Mean SCr (SD), μmol/l

66 (12)

66 (12)

65 (12)

Primary site

 Oral cavity / oropharynx

88 (71)

58 (68)

30 (77)

 Hypopharynx

15 (12)

12 (14)

3 (8)

 Larynx

17 (14)

12 (14)

5 (13)

 Other

4 (3)

3 (4)

1 (3)

Tumor stage

 T1–2

46 (37)

29 (34)

17 (44)

 T3–4

69 (56)

51 (60)

18 (46)

 Unknown

6 (5)

5 (6)

1 (3)

Nodal stage

 N0

15 (12)

12 (14)

3 (8)

 N+

106 (85)

71 (84)

35 (90)

 Unknown

3 (2)

2 (2)

1 (3)

  1. Data given as No. (%), unless otherwise noted
  2. Abbreviations: ECOG Eastern Cooperative Oncology Group Performance Status Score (WHO), CCI Age-adjusted Charlson Comorbidity Index, SCr Serum creatinine (μmol/L), SD standard deviation