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Table 4 Programme sensitivity, interval cancers and Screen detected cancer characteristics of the Population-based Mammographic Screening Programme, Flanders Belgium 2002–2016

From: Flemish breast cancer screening programme: 15 years of key performance indicators (2002–2016)

Performance indicator [EU desirable target]

2002

2003

2004

2005

2006

2007

2008

2009

2010

2011

2012

2013

2014

2015

AAPC all years

APC last segment

%

(95% CI)

Yeara

%

(95% CI)

All cancers (screen detected & interval cancers), N

1071

1229

1147

1215

1407

1317

1450

1486

1543

1732

1702

1848

1726

n.a.

     

Screen detected cancers, N

797

894

789

856

967

888

952

976

1018

1126

1153

1227

1123

1195

     

Programme sensitivity, %

74.4

72.7

68.8

70.5

68.7

67.4

65.7

65.7

66.0

65.0

67.7

66.4

65.1

      

 initial screens, %

74.4

73.0

69.4

71.2

72.3

66.4

65.8

68.5

65.5

67.7

70.6

61.7

61.0

 

−1.3b

(−2.4; −0.1)

2012

−6.5

(− 13.3; + 0.8)

 subsequent irregular screens, %

  

73.0

72.0

70.3

69.0

71.1

73.9

67.0

66.7

71.2

73.8

68.8

 

−0.1

(−1.5; + 1.3)

   

 subsequent regular screens, %

 

68.8

65.9

69.3

65.0

67.7

64.5

62.7

66.0

63.8

66.1

66.6

65.6

 

+ 1.0

(− 0.5; + 2.5)

2005

− 0.4

(−1.2; + 0.5)

Interval cancers, N

274

335

358

359

440

429

498

510

525

606

549

621

603

n.a.

     

 Diagnosed in first year after screening, %

36.9

43.3

38.5

35.7

35.5

33.8

36.5

35.5

34.1

36.3

39.3

39.5

37.1

 

−0.1

(−1.3; + 1.1)

   

 Diagnosed after positive screen, %

22.3

21.5

17.0

12.3

16.6

14.0

16.3

12.9

10.3

11.7

10.0

10.5

9.6

 

−6.4b

(−8.5; −4.2)

   

Interval cancer rate, ‰

3.3

3.4

2.8

2.7

2.7

2.6

2.9

2.8

2.9

3.0

2.8

3.0

3.0

      

 initial screens, ‰

3.3

3.4

3.2

3.2

2.8

3.3

3.7

3.0

3.3

3.1

2.6

3.6

3.6

 

+ 1.5

(−0.3; + 3.4)

   

 subsequent irregular screens, ‰

  

2.5

2.8

2.7

2.7

3.0

2.9

3.4

3.6

3.7

2.9

3.7

 

+ 3.2b

(+ 0.3; + 6.1)

   

 subsequent regular screens, ‰

 

2.9

2.5

2.3

2.6

2.3

2.6

2.7

2.7

2.9

2.7

2.8

2.7

 

+ 0.5

(−0.9; + 1.9)

   

Characteristics screen detected cancers, initial screens

 SDC total, N

797

825

449

373

415

295

287

281

245

262

259

214

210

247

     

  ductal carcinoma in-situ (DCIS), N

140

132

72

59

75

50

58

53

41

64

35

48

35

44

     

  invasive, N

657

693

377

314

340

245

229

228

204

198

224

166

175

203

     

Stage, %

DCIS [10–20%]

17.6

16.0

16.0

15.8

18.1

16.9

20.2

18.9

16.7

24.4

13.5

22.4

16.7

18.2

−1.2

(−3.2; + 0.9)

   

Invasive SDC stage I

40.7

45.0

46.3

48.8

47.0

46.4

42.2

44.1

48.2

42.7

48.6

52.3

43.8

42.9

     

Invasive SDC stage ≥II [< 30%]

24.7

31.0

33.0

30.8

32.3

32.9

36.6

34.9

31.8

31.7

35.9

25.2

38.6

31.2

+ 1.9b

(+ 0.3; + 3.6)

   

Invasive SDC stage unknown

17.1

8.0

4.7

4.6

2.7

3.7

1.0

2.1

3.3

1.1

1.9

0.0

1.0

7.7

     

Nodal status, %

Node - [> 70%]

51.0

61.5

62.9

66.2

62.6

65.3

62.9

67.5

63.7

68.7

64.7

71.7

63.4

61.6

+ 1.7

(−0.3; + 3.7)

2004

+ 0.1

(−0.8; + 1.1)

Node +

20.2

23.5

26.3

22.3

26.8

25.7

32.8

29.4

29.4

28.3

29.0

25.9

30.9

24.6

     

Unknown (invasive SDC)

28.8

15.0

10.9

11.5

10.6

9.0

4.4

3.1

6.9

3.0

6.3

2.4

5.7

13.8

     

Characteristics screen detected cancers, subsequent irregular screens

 SDC total, N

 

3

108

113

137

116

118

136

124

138

161

141

139

175

     

  ductal carcinoma in-situ (DCIS), N

 

0

15

11

15

21

17

21

21

23

28

19

20

25

     

  invasive, N

 

3

93

102

122

95

101

115

103

115

133

122

119

150

     

Stage, %

DCIS

  

13.9

9.7

10.9

18.1

14.4

15.4

16.9

16.7

17.4

13.5

14.4

14.9

+ 3.5

(−1.1; + 8.4)

   

Invasive SDC stage I

  

56.5

62.8

51.8

46.6

47.5

53.7

46.0

49.3

54.7

61.7

54.0

56.6

     

Invasive SDC stage ≥II

  

25.0

23.9

35.8

31.9

37.3

29.4

33.1

33.3

28.0

24.1

31.7

24.6

+ 2.6

(−4.5; + 10.2)

2007

−5.1

(−10.6; + 0.8)

Invasive SDC stage unknown

  

4.6

3.5

1.5

3.4

0.8

1.5

4.0

0.7

0.0

0.7

0.0

4.0

     

Nodal status, %

Node (−)

  

68.8

73.5

63.9

65.3

69.3

72.2

61.2

70.4

72.2

77.0

70.6

66.0

−0.0

(−1.6; + 1.6)

   

Node (+)

  

21.5

17.6

27.0

26.3

28.7

22.6

32.0

26.1

24.8

18.9

26.9

22.0

     

Unknown (invasive SDC)

  

9.7

8.8

9.0

8.4

2.0

5.2

6.8

3.5

3.0

4.1

2.5

12.0

     

Characteristics screen detected cancers, subsequent regular screens

 SDC total, N

 

66

232

370

415

477

547

559

649

726

733

872

774

773

     

  ductal carcinoma in-situ (DCIS), N

 

10

36

70

78

83

95

91

93

106

110

141

120

106

     

  invasive, N

 

56

196

300

337

394

452

468

556

620

623

731

654

667

     

Stage, %

DCIS [10–20%]

 

15.2

15.5

18.9

18.8

17.4

17.4

16.5

14.5

14.6

15.0

16.2

16.1

14.0

+ 2.5

(−1.6; + 6.8)

   

Invasive SDC stage I

 

60.6

52.2

45.7

52.8

52.8

52.1

51.9

56.5

56.5

54.4

56.9

56.7

55.2

     

Invasive SDC stage ≥II [< 25%]

 

21.2

30.2

31.9

24.3

27.0

29.3

30.2

27.4

27.8

29.9

26.1

26.6

24.8

−0.9

(−2.2; + 0.5)

   

Invasive SDC stage unknown

 

3.0

2.2

3.5

4.1

2.7

1.3

1.4

1.5

1.1

0.7

0.8

0.5

6.0

     

Nodal status, %

Node (−) [> 75%]

 

76.8

63.8

64.0

65.6

71.6

71.5

71.4

71.9

73.5

72.7

74.8

74.8

65.4

+ 0.1

(−1.3; + 1.5)

   

Node (+)

 

16.1

25.5

25.7

22.0

22.6

23.2

25.2

23.9

23.2

24.2

22.4

21.7

23.4

     

Unknown (invasive SDC)

 

7.1

10.7

10.3

12.5

5.8

5.3

3.4

4.1

3.2

3.0

2.7

3.5

11.2

     
  1. Numbers in bold are absolute numbers; N.A.: these data exist but are not yet available
  2. AAPC Average Annual Percentage Change, SDC Screen Detected Cancer, DCIS Ductal carcinoma in-situ
  3. athe year of the last joinpoint is the beginning of the last segment
  4. bindicates the (A)APC is significantly different from zero at the alpha = 0.05 level