BMC Cancer

Table 2 Associations between SLC39A6 rs1050631 genotypes and recurrence and survival

From: Involvement of SLC39A6 in gastric adenocarcinoma and correlation of the SLC39A6 polymorphism rs1050631 with clinical outcomes after resection

SNP	Genotype	Recurrence	Unadjusted			Adjusted^a
SNP	Genotype	No(n)/Yes(n)	HR	95%CI	p	HR	95%CI	p
Total (n = 512)		178/334
rs1050631	CC	139/214	1(reference)			1(reference)
	CT	35/104	1.813	1.09–3.01	0.022	1.379	1.090–1.744	0.007
	TT	4/16	1.400	1.11–1.77	0.005	1.441	0.864–2.403	0.161
	CT + TT	39/120	1.440	1.15–1.80	0.001	1.387	1.108–1.735	0.004
SNP	Genotype	Survival	Unadjusted			Adjusteda
		Ali(n)/Dea(n)	HR	95%CI	p	HR	95%CI	p
Total(n = 512)		182/330
rs1050631	CC	143/210	1(reference)			1(reference)
	CT	35/104	1.440	1.138–1.823	0.002	1.416	1.119–1.792	0.004
	TT	4/16	1.947	1.170–3.239	0.010	1.523	0.912–2.542	0.107
	CT + TT	39/120	1.492	1.192–1.868	< 0.001	1.429	1.141–1.790	0.002

The bold values indicate p value < 0.05
Abbreviations: HR hazard ratio, CI Confidence Interval
^aData were calculated using multivariable Cox models that adjusted for gender, age and lymph node metastasis

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