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Table 2 Associations between SLC39A6 rs1050631 genotypes and recurrence and survival

From: Involvement of SLC39A6 in gastric adenocarcinoma and correlation of the SLC39A6 polymorphism rs1050631 with clinical outcomes after resection

SNP

Genotype

Recurrence

Unadjusted

  

Adjusteda

  

No(n)/Yes(n)

HR

95%CI

p

HR

95%CI

p

Total (n = 512)

 

178/334

      

rs1050631

CC

139/214

1(reference)

1(reference)

 

CT

35/104

1.813

1.09–3.01

0.022

1.379

1.090–1.744

0.007

 

TT

4/16

1.400

1.11–1.77

0.005

1.441

0.864–2.403

0.161

 

CT + TT

39/120

1.440

1.15–1.80

0.001

1.387

1.108–1.735

0.004

SNP

Genotype

Survival

Unadjusted

  

Adjusteda

  
  

Ali(n)/Dea(n)

HR

95%CI

p

HR

95%CI

p

Total(n = 512)

 

182/330

      

rs1050631

CC

143/210

1(reference)

1(reference)

 

CT

35/104

1.440

1.138–1.823

0.002

1.416

1.119–1.792

0.004

 

TT

4/16

1.947

1.170–3.239

0.010

1.523

0.912–2.542

0.107

 

CT + TT

39/120

1.492

1.192–1.868

< 0.001

1.429

1.141–1.790

0.002

  1. The bold values indicate p value < 0.05
  2. Abbreviations: HR hazard ratio, CI Confidence Interval
  3. aData were calculated using multivariable Cox models that adjusted for gender, age and lymph node metastasis