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Table 2 Associations between SLC39A6 rs1050631 genotypes and recurrence and survival

From: Involvement of SLC39A6 in gastric adenocarcinoma and correlation of the SLC39A6 polymorphism rs1050631 with clinical outcomes after resection

SNPGenotypeRecurrenceUnadjusted  Adjusteda  
No(n)/Yes(n)HR95%CIpHR95%CIp
Total (n = 512) 178/334      
rs1050631CC139/2141(reference)1(reference)
 CT35/1041.8131.09–3.010.0221.3791.090–1.7440.007
 TT4/161.4001.11–1.770.0051.4410.864–2.4030.161
 CT + TT39/1201.4401.15–1.800.0011.3871.108–1.7350.004
SNPGenotypeSurvivalUnadjusted  Adjusteda  
  Ali(n)/Dea(n)HR95%CIpHR95%CIp
Total(n = 512) 182/330      
rs1050631CC143/2101(reference)1(reference)
 CT35/1041.4401.138–1.8230.0021.4161.119–1.7920.004
 TT4/161.9471.170–3.2390.0101.5230.912–2.5420.107
 CT + TT39/1201.4921.192–1.868< 0.0011.4291.141–1.7900.002
  1. The bold values indicate p value < 0.05
  2. Abbreviations: HR hazard ratio, CI Confidence Interval
  3. aData were calculated using multivariable Cox models that adjusted for gender, age and lymph node metastasis