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Fig. 9 | BMC Cancer

Fig. 9

From: Suppression of nicotinamide phosphoribosyltransferase expression by miR-154 reduces the viability of breast cancer cells and increases their susceptibility to doxorubicin

Fig. 9

Luciferase reporter assay verifying the predicted interaction between miR-154 and 3′-UTR of NAMPT. PsiCHECK2 vector harboring NAMPT 3′-UTR or the mutant form of miR-154 recognition element (NAMPT-MRE-tandem-mut) were co-transfected with microRNA-related oligonucleotides into HEK293T. Firefly luciferase activity was normalized with respect to Renilla luciferase as control. The experiments were repeated at least three times. * P < 0.05, ** P < 0.01

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