Tumor-associated macrophages predict prognosis in diffuse large B-cell lymphoma and correlation with peripheral absolute monocyte count

Table 1 Patient’s demographics according to CD68 and CD163 expression

Characteristics	Patients		CD68 expression			CD163 expression
Characteristics	NO.	%	Low	High	P	Low	High	P
Gender
Female	105	47.5	70	35	0.217	62	43	0.222
Male	116	52.5	68	48		59	57
Age (years)
≤ 60	130	58.8	87	43	0.100	73	57	0.617
>60	91	41.2	51	40		48	43
ECOG-PS
≤ 1	136	61.5	98	38	<0.001	83	53	0.018
>1	85	38.5	40	45		38	47
Extranodal sites of disease
≤ 1	176	79.6	117	59	0.014	103	73	0.026
>1	45	20.4	21	24		18	27
Ann Arbor stage
I/II	127	57.5	93	34	<0.001	80	47	0.004
III/IV	94	42.5	45	49		41	53
LDH
≤ normal	159	71.9	114	45	<0.001	103	56	<0.001
>normal	62	28.1	24	38		18	44
IPI score
0–2	154	69.7	114	40	<0.001	98	56	<0.001
3–5	67	30.3	24	43		23	44
AMC
<460/ul	118	53.4	88	30	<0.001	82	36	<0.001
≥ 460/ul	103	46.6	50	53		39	64

Abbreviations: ECOG-PS Eastern Cooperative Oncology Group performance status, LDH lactate dehydrogenase, IPI International Prognostic Index, AMC absolute monocyte count

ISSN: 1471-2407