Fig. 1
From: Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma
Overexpression of iASPP in GTD. a Photomicrographs showing higher iASPP expression level in hydatidiform moles (HM) than 1st trimester and term placenta as assessed by immunohistochemistry. Scale bar, 100 μm. b Statistically, higher iASPP level was demonstrated in HM than normal placenta (1st trimester and term, *P = 0.017). c Choriocarcinoma cell lines (BeWo, JEG-3 and JAR) showed higher iASPP expression than normal trophoblast cell line, HTR8/SV neo (HTR). Total forms of iASPP (both phospho and unphospho- forms) were detected and their relative intensities normalized with actin were measured by ImageJ and depicted as numbers on the top