Fig. 1From: Autophagy inhibition enhances Matrine derivative MASM induced apoptosis in cancer cells via a mechanism involving reactive oxygen species-mediated PI3K/Akt/mTOR and Erk/p38 signalingMASM induced a dose- and time-dependent inhibitory effect on cell viability. a Chemical structure of matrine and its derivate MASM; b Viability of cells follwoing exposure to different concentrations of MASM for 8 h,12 h and 24 h. Cell viability was determined using MTT assay; c The effect of MASM treatment for 24 h on LDH release. Data are representative of at least three independent experimentsBack to article page