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Fig. 6 | BMC Cancer

Fig. 6

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

Fig. 6

Primary tumor sizes and metastases decreased with GX 15–070 and HCQ treatments. a Adrenal gland of an NSG mouse was injected with 1*106 SK-N-DZ cells. On day 18 after orthotopic injection, a dose of GX 15–070 (3 mg/kg/day) was injected i.p. into mice alone or in combination with HCQ (60 mg/kg/day) for 5 days. Control mice were injected with saline. Right adrenal gland wasn’t injected. b At necropsy, tumor volumes were calculated. LK: Left kidney; RK: Right kidney

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