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Fig. 4 | BMC Cancer

Fig. 4

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

Fig. 4

The effect of GX 15–070 used alone in NB cancer stem cells viability (a) and expression of Bcl-2 in NB CSCs (b). Cells viability of CD133 sorted SK-N-DZ cells treated for 48 h with GX 15–070 were measured using the standard MTT (The statistical difference between CD133high and CD133low was calculated with Fisher’s exact test) (a). Immunoblotting analyses were performed on protein lysates from SK-N-DZ cells. Anti-CD133 and Bcl-2 antibodies were used (b)

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