Fig. 1
From: TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model
Enzalutamide inhibits TMPRSS2-ERG fusion positive cancer cell growth. a Western blot analysis of VCaP Scr shRNA and VCaP ERG shRNA cells for ERG and b-tubulin expression. ERG expression was normalized for b-tubulin and fold differences between VCaP Scr shRNA and VCaP ERG shRNA cells were shown. b Cell growth analysis of VCaP scr shRNA and VCaP ERG shRNA cells treated with 5–20 μM concentrations of enzalutamide for 3, 5 and 7 days. * Indicate the p < 0.05 between groups (DMSO vs. enzalutamide treatment) using student t-test and n = 3