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Table 4 Cox proportional hazards for PSA recurrence-free survival after prostatectomy of established preoperative prognostic parameter and PTPN12 expression

From: High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

Variable

Univariable analysis

Multivariable analysis

Gleason grade biopsy

  ≥ 4 + 4 vs. ≤3 + 3

6.01 (5.41–6.66) ***

4.21 (3.71–4.79) ***

Preoperative PSA-level (ng/μl)

  > 20 vs. < 4

5.12 (4.46–5.89) ***

3.14 (2.61–3.80) ***

cT-stage

 T2c vs. T1c

3.95 (3.24–4.76) ***

2.08 (1.66–2.58) ***

PTPN12 expression

 Strong vs. negative

1.85 (1.53–2.23) ***

1.71 (1.40–2.07) ***

 ERG negative subset

2.50 (1.82–3.35) ***

2.28 (1.65–3.09) ***

 ERG positive subset

1.51 (1.23–2.02) *

1.37 (1.01–1.85) *

  1. Confidence interval (95%) in brackets; asterisk indicate significance level: * p ≤ 0.05, ** p ≤ 0.001, *** p ≤ 0.0001; ERG ETS-related gene
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BMC Cancer

ISSN: 1471-2407

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