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Table 3 Univariate and multivariate analysis for prognostic factors in 351 cases of PC patients with curatively surgical resection

From: The diversity between curatively resected pancreatic head and body-tail cancers based on the 8th edition of AJCC staging system: a multicenter cohort study

Parameters median survival (days) Univariate analysis P (log rank) Multivariate analysis hazard ratio (95% CI) P
Age (< 65/ ≥65 years) 432/421 0.127  
Gender (male/female) 421/472 0.366  
Tumor location (ph/pbt) 488/340 0.003 1.405(1.082–1.826) 0.011
Tumor size (< 2/ ≥2 cm) 472/421 0.371  
Tumor size (< 3/ ≥3 cm) 472/418 0.096  
Well/Moderate/poor Differentiation 452/420/382 0.071  
T stage (T1 + T2/ T3 + T4) 472/381 0.068  
Lymph nodes metastasis 8th (N0/N1/N2) 480/330/284 0.001 1.451(1.123–1.874) 0.004
Lymph nodes metastasis 7th (N0/N1 + N2)a 472/399 0.090  
8th AJCC stage (I + II /III + VI) 468/284 0.007 1.442(1.085–1.915) 0.012
Perineural invasion (absent/present) 454/400 0.179  
Vascular permeation (absent/present) 480/330 0.004 1.401(0.905–2.168) 0.131
CA19–9 level (< 37 U/ml/ ≥37 U/ml) 565/395 0.104  
PLM (absent/present) 499/330 0.000 1.594(1.224–2.076) 0.001
 7th AJCC stage 468/172 0.012 Not included  
  1. N1 Lymph nodes metastasis 1–3; N2 Lymph nodes metastasis> 3; 7th and 8th AJCC stage 7th and 8th edition of AJCC staging system in PC; Ph Pancreatic head; Pbt Pancreatic body-tail. a In 7th AJCC stage, N1 and N2 combined together