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Table 3 Clinicopathological data of gliomas patients based on the molecular subgroups

From: Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylation

Variable No Glioma Molecular subgroups
GBM, IDH wildtype GBM, IDH mutant 1p/19q codeleted gliomas Astrocytoma, IDH wildtype Astrocytoma, IDH mutant
Number of samples 403 245 11 49 43 55
Age of diagnosis (years) Median 63.0 44.0 48.5 57.0 38.0
Minimum 18.0 17.0 27.0 16.0 23.0
Maximum 87.0 59.0 76.0 80.0 66.0
Sex Male 163 5 34 24 32
Female 82 6 15 19 23
Ratio (M/F) 2:1 0.8:1 2:1 1.3:1 1.4:1
Adjuvant Therapy Receveid 211 11 30 27 45
None 19 0 1 6 3
No data 15 0 18 10 7