Fig. 2From: Clinical insights gained by refining the 2016 WHO classification of diffuse gliomas with: EGFR amplification, TERT mutations, PTEN deletion and MGMT methylationFrequency of EGFR amplification (amp), PTEN deletion (del), TERT promoter mutations (mut) and MGMT promoter methylated samples in the distinct glioma molecular subgroups. EGFR amplification was analyzed: in 227 GBM-IDH wildtype, 9 GBM IDH-mutant, 48 1p/19q codeleted gliomas, 35 Astrocytoma IDH-wildtype, 53 Astrocytomas IDH-mutant. PTEN deletion was analyzed: in 225 GBM IDH-wildtype, 7 GBM IDH-mutant, 48 1p/19q codeleted gliomas, 37 Astrocytoma IDH-wildtype and 53 Astrocytoma IDH-mutant. TERT promoter mutations were analyzed: in 124 GBM IDH-wildtype, 4 GBM IDH-mutant, 49 1p/19q codeleted gliomas, 41 Astrocytoma IDH-wildtype, 51 Astrocytoma IDH-mutant. MGMT methylation was analyzed: in 235 GBM IDH-wildtype, 10 GBM IDH-mutant, 49 1p/19q codeleted gliomas, 41 Astrocytoma IDH-wildtype and 54 Astrocytoma IDH-mutantBack to article page