From: Tubal ligation and endometrial Cancer risk: a global systematic review and meta-analysis
First author | DOP | SS | Design | Country | Population | Study quality* | # of cases in TL+ | # of TL+ | # of cases in TL- | # of TL- | TES | ES | UL | LL | AES | UL | LL | Adjusted for: |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Castellsague X 14 | 1996 | 3634 | Case control | USA | 20 to 54 years | High | 53 | 671 | 383 | 2963 | OR | 0.58 | 0.43 | 0.78 | 0.87 | 0.63 | 1.2 | Age and Parity |
Lacey JV Jr. 16 | 2000 | 701 | Case control | USA | 20 to 74 years | High | 47 | 87 | 357 | 614 | OR | 0.9 | 0.6 | 1.4 | 1.4 | 0.8 | 2.3 | Age, parity, and OC usage |
Kjaer SK 17 | 2004 | 65,232 | Cohort | Denmark | Women who had a tubal sterilization (1977–1993) | High | 30 | 65,232 | – | – | SIR | 0.7 | 0.5 | 1 | – | – | – | – |
Rosenblatt KA 15 | 1997 | 1454 | Case control | Seven countries | Older than 15 | Moderate | 35 | 377 | 101 | 1077 | OR | – | – | – | 1.26 | 0.79 | 2 | Parity and age, hospital and date of diagnosis |
Wernli KJ 11 | 2006 | 259,640 | Cohort | China | Women employed in the textile industry | Moderate | 59 | – | 147 | – | HR | – | – | – | 1.1 | 0.79 | 1.56 | Age at baseline and reproductive category |
Nagle CM 6 | 2008 | 1650 | Case control | Australia | Cancer registries | Moderate | 19 | 425 | 404 | 1225 | OR | – | – | – | 0.4 | 0.3 | 0.7 | Age, education, parity and hormone contraceptive use |
Iversen L 18 | 2007 | 5602 | Cohort | United Kingdom | Women who were using oral contraceptives | High | 1 | 2801 | 4 | 2801 | – | – | – | – | – | – | – | – |
Gaitskell K 10 | 2016 | 1,278,783 | Cohort | United Kingdom | UK women | High | 2018 | 206,233 | 8571 | 767,251 | RR | – | – | – | 0.98 | 0.93 | 1.03 | Age, region, socioeconomic status, parity, age at first birth, hysterectomy, smoking, alcohol intake, physical activity, body mass index, and use of the oral, contraceptive pill or menopausal hormones |
Winer I 9 | 2016 | 76,483 | Cohort | USA | 50 to 79 years, postmenopausal | High | 192 | 14,499 | 945 | 61,984 | HR | 0.87 | 0.75 | 1.05 | 0.9 | 0.76 | 1.07 | Age stratum at randomization and region |
Falconer H 2 | 2018 | 5,385,186 | Cohort | Switzerland | Swedish women | High | 281 | 80,765 | 35,430 | 5,304,421 | HR | – | – | – | 0.73 | 0.65 | 0.83 | Age, parity, calendar time and education status |