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Table 1 The IC50 values (μM) of BM-1197 in NHL cell lines

From: A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway

Cell line

IC50 (μmol/L)

OCI-ly1

0.47 ± 0.06

OCI-Ly8

0.19 ± 0.04

OCI-ly19

0.22 ± 0.03

Su-DHL-4

0.72 ± 0.16

Nu-DHL-1

2.99 ± 0.36

Raji

5.94 ± 0.04

Romas

3.86 ± 0.99

Namalwa

3.26 ± 0.5

Jurkat

2.16 ± 0.4

  1. Data are the mean ± SEM of three independent experiments