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Table 1 Relationship of FGFR3 with different clinicopathologic parameters of melanoma patients

From: FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

Parameters

FGFR3 expression

n

Low

High

P

Age

 ≤ 60

29

19

10

NS

 > 60

13

7

6

 

Gender

 Male

25

17

8

NS

 Female

17

9

8

 

Location

 Head/neck

2

1

1

NS

 Trunk

29

18

11

 

 Extremities

8

5

3

 

 Feet

3

2

1

 

Breslow thickness

 1.01–2.00

14

12

2

0.0119

 2.01–4.00

15

6

9

 

  > 4.00

13

8

5

 

Clark Classification

 I-II

9

6

3

NS

 III-IV

33

20

13

 

Ulceration

 Yes

20

10

10

NS

 No

22

16

6

 

Nodular

 Yes

17

9

8

NS

 No

25

17

8

 

SLN status

 Not involved

27

21

6

0.0045

 Involved

15

5

10

 
  1. Note: NS No significance, SNL Sentinel lymph node