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Fig. 3 | BMC Cancer

Fig. 3

From: FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

Fig. 3

The colony formation ability and apoptosis rate of A357 cells. a left panel, colonies formed by A357 cells transfected with LV-shFGFR3 or LV-control; right panel, comparison of the numbers of colonies formed by A357 cells transfected with LV-shFGFR3 or LV-control; b left panel, colonies formed by A357 cells transfected with pcDNA3.0-FGFR3 or the control plasmids; right panel, comparison of the numbers of colonies formed by A357 cells transfected with pcDNA3.0-FGFR3 or the control plasmids; c left panel, dot-plots of cell apoptosis measured by flow cytometry; right panel, comparison of the apoptosis rates among A357 cells transfected with LV-shFGFR3, LV-control, pcDNA3.0-FGFR3, or the control plasmids for pcDNA3.0-FGFR3; d Western blot analysis of different forms of caspase3; e comparison of caspase 3 activity in A357 cells transfected with LV-shFGFR3, LV-control, pcDNA3.0-FGFR3, or the control plasmids (* p < 0.05;* * p < 0.01)

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