Fig. 2From: FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFRExpression of FGFR3 and the proliferation ability in A357 cells transfected with a lentivirus containing shFGFR3 or pcDNA3.0-FGFR3. a comparison of GFR3 mRNA levels in A357 cells transfected with lentivirus containing shFGFR3 with A357 cells transfected with a control vector; b GFR3 protein was detected by Western blot in A357 cells transfected with lentivirus containing shFGFR3 and A357 cells transfected with a control vector; c comparison of FGFR3 mRNA levels in A357 cells transfected with pcDNA3.0-FGFR3 with A357 cells transfected with a control plasmid; d GFR3 protein detected by Western blot in A357 cells transfected with pcDNA3.0-FGFR3 and A357 cells transfected with control plasmids; e time course of the viability of A357 cells transfected with LV-shFGFR3 or LV-control; f time course of the viability of A357 cells transfected with pcDNA3.0-FGFR3 or the control plasmid (* p < 0.05; * * p < 0.01)Back to article page