DMFS | LRFS | PFS | OS | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
B | HR(95%CI) | P | B | HR (95%CI) | P | B | HR (95%CI) | P | B | HR (95%CI) | P | |
Gender | ||||||||||||
Female | 1 | 1 | 1 | 1 | ||||||||
Male | −0.934 | 0.393 (0.188–0.823) | 0.013 | 0.247 | 1.280 (0.733–2.237) | 0.385 | −0.205 | 0.815 (0.549–1.210) | 0.310 | −0.523 | 0.592 (0.347–1.011) | 0.055 |
Age | ||||||||||||
<44 | 1 | 1 | 1 | 1 | ||||||||
≥ 44 | −0.096 | 0.909 (0.582–1.421) | 0.675 | −0.439 | 0.645 (0.393–1.058) | 0.082 | −0.256 | 0.774 (0.571–1.050) | 0.100 | −0.252 | 0.777 (0.534–1.132) | 0.189 |
Tumor stage | ||||||||||||
T1 | 1 | 1 | 1 | 1 | ||||||||
T2 | 0.149 | 1.161 (0.335–4.026) | 0.814 | −0.229 | 0.795 (0.113–5.603) | 0.818 | −0.200 | 0.819 (0.287–2.339) | 0.709 | 0.206 | 1.229 (0.407–3.714) | 0.715 |
T3 | −0.894 | 0.409 (0.128–1.305) | 0.131 | 0.109 | 1.116 (0.246–5.065) | 0.887 | −0.510 | 0.600 (0.256–1.405) | 0.240 | −0.546 | 0.580 (0.215–1.561) | 0.280 |
T4 | −0.474 | 0.623 (0.248–1.562) | 0.313 | −0.329 | 0.720(0.175–2.954) | 0.648 | −0.664 | 0.515 (0.243–1.091) | 0.083 | −0.632 | 0.531 (0.231–1.223) | 0.137 |
Node stage | ||||||||||||
N0 | 1 | 1 | 1 | 1 | ||||||||
N1 | −1.979 | 0.138 (0.046–0.418) | < 0.001 | −1.437 | 0.238 (0.047–1.210) | 0.083 | −1.603 | 0.201 (0.088–0.458) | < 0.001 | −1.509 | 0.221 (0.086–0.567) | 0.002 |
N2 | −2.251 | 0.105 (0.043–0.260) | < 0.001 | −0.594 | 0.552 (0.160–1.902) | 0.347 | −1.329 | 0.265 (0.138–0.508) | < 0.001 | −1.242 | 0.289 (0.141–0.594) | 0.001 |
N3 | −1.330 | 0.264 (0.111–0.629) | 0.003 | −0.329 | 0.720(0.204–2.542) | 0.609 | −0.876 | 0.416 (0.216–0.804) | 0.009 | −0.800 | 0.449 (0.216–0.934) | 0.032 |
Clinical stage | ||||||||||||
III | 1 | 1 | 1 | 1 | ||||||||
IV | 0.224 | 1.251 (0.436–3.593) | 0.677 | −0.052 | 0.950 (0.212–4.254) | 0.946 | 0.080 | 1.083 (0.482–2.434) | 0.847 | −0.448 | 0.639 (0.256–1.598) | 0.338 |
Target therapy | ||||||||||||
Without | 1 | 1 | 1 | 1 | ||||||||
With | 0.840 | 2.317 (1.224–4.384) | 0.010 | −0.339 | 0.712 (0.427–1.189) | 0.194 | 0.353 | 1.423 (0.985–2.058) | 0.060 | 0.754 | 2.125 (1.269–3.560) | 0.004 |
Induction chemotherapy | ||||||||||||
No | 1 | 1 | 1 | 1 | ||||||||
Yes | 0.303 | 1.354 (0.849–2.159) | 0.203 | −0.209 | 0.811 (0.471–1.398) | 0.451 | 0.031 | 1.031 (0.742–1.434) | 0.855 | −0.012 | 0.988 (0.655–1.490) | 0.955 |