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Table 5 Multivariate analysis of variables correlated with the treatment regimen status and other significant prognostic factors in 730 eligible cases

From: The long-term survival of patients with III-IVb stage nasopharyngeal carcinoma treated with IMRT with or without Nimotuzumab: a propensity score-matched analysis

 

DMFS

LRFS

PFS

OS

B

HR(95%CI)

P

B

HR (95%CI)

P

B

HR (95%CI)

P

B

HR (95%CI)

P

Gender

 Female

1

  

1

  

1

  

1

  

 Male

−0.934

0.393 (0.188–0.823)

0.013

0.247

1.280 (0.733–2.237)

0.385

−0.205

0.815 (0.549–1.210)

0.310

−0.523

0.592 (0.347–1.011)

0.055

Age

 <44

1

  

1

  

1

  

1

  

  ≥ 44

−0.096

0.909 (0.582–1.421)

0.675

−0.439

0.645 (0.393–1.058)

0.082

−0.256

0.774 (0.571–1.050)

0.100

−0.252

0.777 (0.534–1.132)

0.189

Tumor stage

 T1

1

  

1

  

1

  

1

  

 T2

0.149

1.161 (0.335–4.026)

0.814

−0.229

0.795 (0.113–5.603)

0.818

−0.200

0.819 (0.287–2.339)

0.709

0.206

1.229 (0.407–3.714)

0.715

 T3

−0.894

0.409 (0.128–1.305)

0.131

0.109

1.116 (0.246–5.065)

0.887

−0.510

0.600 (0.256–1.405)

0.240

−0.546

0.580 (0.215–1.561)

0.280

 T4

−0.474

0.623 (0.248–1.562)

0.313

−0.329

0.720(0.175–2.954)

0.648

−0.664

0.515 (0.243–1.091)

0.083

−0.632

0.531 (0.231–1.223)

0.137

Node stage

 N0

1

  

1

  

1

  

1

  

 N1

−1.979

0.138 (0.046–0.418)

< 0.001

−1.437

0.238 (0.047–1.210)

0.083

−1.603

0.201 (0.088–0.458)

< 0.001

−1.509

0.221 (0.086–0.567)

0.002

 N2

−2.251

0.105 (0.043–0.260)

< 0.001

−0.594

0.552 (0.160–1.902)

0.347

−1.329

0.265 (0.138–0.508)

< 0.001

−1.242

0.289 (0.141–0.594)

0.001

 N3

−1.330

0.264 (0.111–0.629)

0.003

−0.329

0.720(0.204–2.542)

0.609

−0.876

0.416 (0.216–0.804)

0.009

−0.800

0.449 (0.216–0.934)

0.032

Clinical stage

 III

1

  

1

  

1

  

1

  

 IV

0.224

1.251 (0.436–3.593)

0.677

−0.052

0.950 (0.212–4.254)

0.946

0.080

1.083 (0.482–2.434)

0.847

−0.448

0.639 (0.256–1.598)

0.338

Target therapy

 Without

1

  

1

  

1

  

1

  

 With

0.840

2.317 (1.224–4.384)

0.010

−0.339

0.712 (0.427–1.189)

0.194

0.353

1.423 (0.985–2.058)

0.060

0.754

2.125 (1.269–3.560)

0.004

Induction chemotherapy

 No

1

  

1

  

1

  

1

  

 Yes

0.303

1.354 (0.849–2.159)

0.203

−0.209

0.811 (0.471–1.398)

0.451

0.031

1.031 (0.742–1.434)

0.855

−0.012

0.988 (0.655–1.490)

0.955