From: Sarcomatoid carcinoma presenting as cancers of unknown primary: a clinicopathological portrait
Variable | Patients N (%) (N = 48) |
---|---|
Age (years) | |
Median | 59 |
Gender | |
Female | 28 (58.3%) |
Male | 20 (41.7%) |
Performance status (ECOG) | |
0 | 8 (21.1%) |
1 | 13 (34.2%) |
2 | 10 (26.3%) |
3+ | 7 (18.4%) |
Number of metastatic sites | |
1 | 15 (31.3%) |
2 | 8 (16.7%) |
3+ | 25 (52%) |
Lactate dehydrogenase (IU/L) | |
Normal (≤ 618) | 33 (75%) |
High (> 618) | 11 (25%) |
Neutrophil-lymphocyte ratio | |
Low (≤ 5) | 33 (71.7%) |
High (> 5) | 13 (28.3%) |
Sites of metastasis | |
Lung | 13 (27.1%) |
Liver | 10 (20.8%) |
Bone | 20 (41.7%) |
Lymph node | 24 (50%) |
First line treatment | |
Surgery | 9 (26.5%) |
Radiation | 8 (23.5%) |
Gemcitabine + Docetaxel | 6 (17.6%) |
Taxane + Platinum | 4 (11.8%) |
Gemcitabine + Platinum | 3 (8.8%) |
Other chemotherapy | 4 (11.8%) |