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Table 2 Uni- and multivariable analysis for LNM/LVI of EGC patients in the training set

From: Risk factors of lymph node metastasis or lymphovascular invasion for early gastric cancer: a practical and effective predictive model based on international multicenter data

Parameters Univariable Analysis Multivariable Analysis
Odds Ratio (95%CI) P-value Odds Ratio (95%CI) P-value
Age
 ≤ 60 Ref    
 > 60 0.997 (0.776–1.282) 0.984   
Sex
 Male Ref   Ref  
 Female 1.476 (1.135–1.92) 0.004 1.492 (1.134–1.963) 0.004
Tumor location   0.714   
 Upper Ref    
 Middle 1.117 (0.765–1.63) 0.568   
 Lower 1.001 (0.695–1.443) 0.994   
 Overlapa 1.28 (0.739–2.217) 0.378   
Tumor size
 ≤ 20 mm Ref   Ref  
 > 20 mm 1.73 (1.346–2.224) <  0.001 1.536 (1.184–1.992) 0.001
Depth of invasion
 Mucosa Ref   Ref  
 Submucosa 2.939 (2.22–3.892) <  0.001 2.898 (2.177–3.858) <  0.001
Tumor histological types
 Differentiated Ref   Ref  
 Undifferentiated 2.03 (1.52–2.71) <  0.001 1.983 (1.474–2.668) <  0.001
  1. Abbreviations: Ref reference, CI confidence interval, LVI lymphovascular invasion, EGC early gastric cancer, LNM lymph node metastasis
  2. aOverlap, tumor invaded two or more regions simultaneously
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