Fig. 1From: Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicaseEffects of the derivatives of tetrandrine and fangchinoline on dsDNA binding of BLM642–1290 helicase. Note: A0 is the fluorescence anisotrophy of dsDNA binding small molecules. A1 is the fluorescence anisotrophy of the complexes which is formed by BLM642–1290 binding dsDNA and small molecules. Δ(A1-A0) is the differences between the activities of BLM helicase binding dsDNA which is treated by small molecules or not. Data were means ± SD with five replicates and the same belowBack to article page