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Fig. 1 | BMC Cancer

Fig. 1

From: Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicase

Fig. 1

Effects of the derivatives of tetrandrine and fangchinoline on dsDNA binding of BLM642–1290 helicase. Note: A0 is the fluorescence anisotrophy of dsDNA binding small molecules. A1 is the fluorescence anisotrophy of the complexes which is formed by BLM642–1290 binding dsDNA and small molecules. Δ(A1-A0) is the differences between the activities of BLM helicase binding dsDNA which is treated by small molecules or not. Data were means ± SD with five replicates and the same below

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