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Table 3 Study quality of the diagnostic studies, as judged by the QUADAS II checklist

From: A pair-wise meta-analysis highlights circular RNAs as potential biomarkers for colorectal cancer

Study Risk of bias Concerns regarding applicability Total stars
Patient selection Index test Reference standard Flow and timing Patient selection Index test Reference standard
Wang J 2018 [9] Low Unclear Low Low Unclear Low Low 5
Wang F 2018 [10] Low Unclear Low Unclear Unclear Low Low 4
Wang X 2015 [11] Low Unclear Low Low Unclear Low Low 5
Hsiao KY 2017 [12] Low Unclear Low Unclear Unclear Low Low 4
Zhang P 2017 [13] Low Unclear Low Unclear Unclear Low Low 4
Li J 2018 [14] Low Unclear Low Unclear Unclear Low Low 4
Ji WX 2018 [16] Low Unclear Low Unclear Unclear Low Low 4
Li XN 2019 [19] Low Low Low Low Unclear Low Low 6
Zhuo F 2017 [20] Low Low Low Low Unclear Low Low 6
  1. QUADAS Quality Assessment for Studies of Diagnostic Accuracy