Stromal ColXα1 expression correlates with tumor-infiltrating lymphocytes and predicts adjuvant therapy outcome in ER-positive/HER2-positive breast cancer

Table 2 Spearman and Pearson Correlations of ColXα1 with Tumor Immune Environment

Characteristic	Pearson with ColXα1	P-value
RIH dataset	ColXα1 IHC
TILs	−0.47	< 0.001
Age	0.099	0.21
TCGA (ER/HER2 only, N = 102) Spearman with ColXα1 RNA-seq
Naïve B Cells	−0.29	0.003
CD 8 T Cells	−0.36	< 0.001
Monocytes	−0.28	0.005
Lymphocytes	−0.41	< 0.001
Macrophages	0.40	< 0.001
TIL Percentage	−0.01	0.32

ISSN: 1471-2407