Table 3 Genotype frequencies of SNPs and Hardy-Weinberg equilibrium in studied populations
Genotypes | Control group | GC patients | ||||||
|---|---|---|---|---|---|---|---|---|
No. (%) | HWE | No. (%) | HWE | All type GCa | ||||
|  | χ2 | P value | χ2 | P value | χ2 | P value | ||
rs2273535 | 203 | 0.867 | 0.351 | 110 | 0.366 | 0.544 | 3.987 | 0.136 |
 AA | 120 (59.1) |  |  | 77 (70.0) | ||||
 AT | 69 (34.0) | 29 (26.4) | ||||||
 TT | 14 (6.9) | 4 (3.6) | ||||||
rs1047972 | 202 | 0.152 | 0.696 | 113 | 1.691 | 0.193 | 4.840 | 0.089 |
 CC | 148 (73.3) |  |  | 95 (84.1) | ||||
 CT | 49 (24.2) | 16 (14.1) | ||||||
 TT | 5 (2.5) | 2 (1.8) | ||||||
rs911160 | 201 | 0.349 | 0.554 | 116 | 2.815 | 0.093 | 6.233 | 0.044 |
 GG | 107 (53.2) |  |  | 70 (60.4) | ||||
 CG | 77 (38.3) | 44 (37.9) | ||||||
 CC | 17 (8.5) | 2 (1.7) | ||||||
rs8173 | 200 | 0.017 | 0.895 | 115 | 0.0001 | 0.989 | 8.007 | 0.018 |
 CC | 97 (48.5) |  |  | 39 (33.9) | ||||
 CG | 84 (42.0) | 56 (48.7) | ||||||
 GG | 19 (9.5) | 20 (17.4) | ||||||
rs2241909 | 203 | 1.186 | 0.276 | 115 | 1.065 | 0.302 | 6.201 | 0.102 |
 AA | 87 (42.9) |  |  | 63 (54.8) | ||||
 AG | 97 (47.8) | 47 (40.9) | ||||||
 GG | 19 (9.3) | 5 (4.3) | ||||||
rs2289590 | 200 | 3.523 | 0.060 | 108 | 1.414 | 0.234 | 20.683 | < 0.001 |
 AA | 62 (31.0) |  |  | 60 (55.6) | ||||
 AC | 110 (55.0) | 44 (40.7) | ||||||
 CC | 28 (14.0) | 4 (3.7) | ||||||
rs758099 | 203 | 2.107 | 0.146 | 116 | 1.186 | 0.276 | 3.107 | 0.211 |
 CC | 103 (50.8) |  |  | 57 (49.2) | ||||
 CT | 77 (37.9) | 52 (44.8) | ||||||
 TT | 23 (11.3) | 7 (6.0) | ||||||
rs11084490 | 201 | 0.0009 | 0.975 | 115 | 3.038 | 0.083 | 9.083 b | 0.009 |
 CC | 121 (60.2) |  |  | 83 (72.2) | ||||
 CG | 70 (34.8) | 32 (27.8) | ||||||
 GG | 10 (5.0) | – | ||||||
rs42873 | 201 | 0.272 | 0.601 | 115 | 2.668 | 0.102 | 3.228 | 0.199 |
 GG | 127 (63.2) |  |  | 65 (56.5) | ||||
 CG | 64 (31.8) | 47 (40.9) | ||||||
 CC | 10 (5.0) | 3 (2.6) | ||||||