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Table 6 Most common grade 3–5 adverse events and adverse events of special interest with cisplatin (related and unrelated events; safety population); Results are presented as number of patients and all the side-effects were evaluated according to CTCAE v4.0

From: Prophylactic HIPEC with radical D2 gastrectomy improves survival and peritoneal recurrence rates for locally advanced gastric cancer: personal experience from a randomized case control study

ComplicationHIPEC Group (n = 40)Control Group (n = 40)
Neutropenia12
Anastomotic Leak01
Bowel Obstruction01
Renal Toxicity11
Liver Function Dysfunction02
Hyperbilirubinemia12
Post-operative Infection01
Surgical Wound Dehiscence01
Total Perioperative Side-effects311