Table 6 Most common grade 3–5 adverse events and adverse events of special interest with cisplatin (related and unrelated events; safety population); Results are presented as number of patients and all the side-effects were evaluated according to CTCAE v4.0
Complication | HIPEC Group (n = 40) | Control Group (n = 40) |
|---|---|---|
Neutropenia | 1 | 2 |
Anastomotic Leak | 0 | 1 |
Bowel Obstruction | 0 | 1 |
Renal Toxicity | 1 | 1 |
Liver Function Dysfunction | 0 | 2 |
Hyperbilirubinemia | 1 | 2 |
Post-operative Infection | 0 | 1 |
Surgical Wound Dehiscence | 0 | 1 |
Total Perioperative Side-effects | 3 | 11 |