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Table 1 Distribution of reproductive and tumor characteristics among case women with any methylation marker (N = 855) and among all case women in a population-based study (N = 1508), Long Island Breast Cancer Study Project

From: Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer

 

Patients with any methylation marker

All patients

(Total N = 855)

(Total N = 1508)

N (%)

N (%)

Age at diagnosis

 < 50 years

215 (25.1)

407 (27.0)

 ≥ 50 years

640 (74.9)

1101 (73.0)

Menopausal status

 premenopausal

244 (29.2)

472 (31.9)

 postmenopausal

593 (70.8)

1006 (68.1)

 missing

18

30

Age at Menarche

 ≤ 12 years

372 (44.0)

658 (44.0)

 > 12 years

473 (56.0)

837 (56.0)

 missing

10

13

Parity

 Nulliparous

119 (13.9)

198 (13.1)

 Parous

736 (86.1)

1310 (86.9)

Age at First Birth (among parous women only)

 ≤ 23 years

242 (32.9)

437 (33.4)

 23–27 years

241 (32.7)

430 (32.9)

 ≥ 27 years

253 (34.4)

442 (33.8)

 missing

0

1

Lactaction (among parous women only)

 Never

462 (62.8)

830 (63.4)

 Ever

274 (37.2)

480 (36.6)

Tumor Stage

 In Situ

104 (12.2)

235 (15.6)

 Invasive

751 (87.8)

1273 (84.4)

ER Status

 Positive

478 (76.2)

726 (73.3)

 Negative

149 (23.8)

264 (26.7)

 missing

228

518

PR Status

 Positive

399 (63.6)

635 (64.1)

 Negative

228 (36.3)

355 (35.9)

 missing

228

518