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Table 1 Univariable analysis for progression-free survival

From: Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG0304

Univariable

Factors

Category

Univariable analysis

  

HR (95% CI)

p-value

Sex

Female (vs. Male)

0.61 (0.27–1.38)

0.23

Age (Years)

≥40 (vs. < 40)

2.04 (0.76–5.47)

0.16

Performance Status

1 (vs. 0)

1.11 (0.46–2.69)

0.81

Histological subtype

Leiomyosarcoma (vs. UPS)

0.59 (0.18–1.98)

0.40

 

Synovial sarcoma (vs. UPS)

0.34 (0.10–1.12)

0.08

 

Others (vs. UPS)

0.64 (0.24–1.72)

0.38

Tumor differentiation

3 (vs. 2)

0.64 (0.29–1.43)

0.28

Tumor necrosis

1 or 2 (vs. 0)

1.28 (0.56–2.93)

0.56

Tumor mitosis

2 or 3 (vs. 1)

1.14 (0.51–2.57)

0.75

Histological grade (FNCLCC)

Grade 3 (vs. 2)

0.94 (0.42–2.09)

0.87

Histological grade (Ki-67)

Grade 3 (vs. 2)

1.38 (0.61–3.12)

0.43

Tumor size

> 10 cm (vs. < 10 cm)

3.15 (1.37–7.21)

0.0067

  1. Abbreviations: HR hazard ratio, CI confidence interval, UPS, undifferentiated pleomorphic sarcoma, FNCLCC French Federation of Cancer Center