Fig. 5

The lentivirus-mediated CDglyTK fusion gene by intra-artery perfusion effectively suppresses transplanted breast cancer in vivo. (upper left panel) Tumor growth curve. (upper middle panel) Appearance and (upper right panel) weight of transplanted tumors at 42 days after treatment. (lower panel) Histology analysis of the transplanted tumors by hematoxylin and eosin (H&E) staining. Scale bar: 100 μm. Data was shown as the mean ± SD of six independent samples. **P < 0.01; ***P < 0.001. LV-CDglyTK, flaps transfected with lentivirus-mediated CDglyTK gene; LV-GFP, flaps transfected with empty lentivirus; Control, non-transfected flaps