Fig. 4From: Oncogenic Akt-FOXO3 loop favors tumor-promoting modes and enhances oxidative damage-associated hepatocellular carcinogenesisEnhanced proliferation and elevated expression of AFP and Vimentin in livers of DEN-injected 40-week-old FOXO3CAHep transgenic mice. a Representative IHC staining for Ki67, AFP, p53, E-Cadherin, N-Cadherin, and Vimentin in 40-week-old DEN-injected control and DEN-injected FOXO3CAHep transgenic mice (bar = 100 μm). b Scoring of Ki67-positivity (n = 4). c Western blot analysis in livers from 40-week-old DEN-injected control and DEN-injected FOXO3CAHep transgenic mice with AFP, c-Myc, p53, E-Cadherin, N-Cadherin, Vimentin and GAPDH as loading control (upper part), as well as densitometric quantification (lower part)Back to article page