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Table 3 Multivariate analyses

From: Maximal standard uptake values of 18F-fluoro-2-deoxy-D-glucose positron emission tomography compared with Epstein-Barr virus DNA as prognostic indicators in de novo metastatic nasopharyngeal carcinoma patients

 

Model 1

Model 2

Model 3

Characteristic

HR (95%CI)

P value

HR (95%CI)

P value

HR (95%CI)

P value

SUVmax-T

 

NS

 

NS

 

NS

SUVmax-N

1.40(0.95–2.06)

0.087

 

NS

 

NS

SUVmax-M

1.72(1.13–2.78)

0.012

1.72(1.10–2.67)

0.017

 

NS

EBV-DNA

  

1.62(1.08–2.43)

0.020

1.55(1.03–2.32)

0.036

Metastatic site

      

 Lung vs. Bone

    

0.74(0.38–1.41)

0.357

 Liver vs. Bone

    

1.10(0.52–2.32)

0.805

 Distant nodes vs. Bone

    

0.50(0.18–1.39)

0.184

 Multiple vs. Bone

    

1.87(1.25–2.80)

0.002

LRRT

    

0.51(0.35–0.78)

< 0.001

  1. Abbreviations: NS non-significant, HR hazard ratio, CI confidence interval, LRRT locoregional radiotherapy
  2. Backward step-wise multivariate analyses using Cox proportional hazard model was applied to select variables. Only variables that were significant associated with overall survival are presented
  3. HRs were calculated for SUVmax-T (> 17.0 vs. ≤17.0); SUVmax-N (> 12.7 vs. ≤12.7); SUVmax-M (> 6.9 vs. ≤6.9); EBV DNA (> 13,800 copies/ml vs. ≤13,800 copies/ml); LRRT (Yes vs. No)
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BMC Cancer

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