Table 1 Summary of primary and secondary outcomes
Type | Outcome | Measurement |
|---|---|---|
Primary Outcome | Cluster-level mean number of ED + H visits per patient | Counts extracted from healthcare administrative data |
Patient Reported Outcomes (Secondary Outcomes) | Severity of chemotherapy treatment toxicities | National Cancer Institute Patient-reported Outcomes Common Terminology Criteria for Adverse Events (NCI-PRO-CTCAE) |
Self-care for management of chemotherapy toxicities | Leuven Questionnaire for Patient Self-Care during Chemotherapy (L-PaSC) | |
Self-efficacy (confidence) for managing symptoms | Stanford Self-Management Self-Efficacy | |
Quality of life (including anxiety and depression) | − Patient Health Questionnaire (PHQ-9) − Generalized Anxiety Disorder (GAD-7) − Functional Assessment for Cancer Therapy for Patients with Breast Cancer (FACT-B) − EQ-5D-3 L | |
Coordination of care | Adapted Picker Survey | |
Cost-effectiveness of pro-active toxicity management compared to routine care (control arm) | − Healthcare administrative data − EQ-5D-3 L |