| |
Model 3.0 (M3.0)
|
Model 3.1
|
Model 3.2
|
Model 3.3
|
|---|
|
M3.0 + perf. Status
|
M3.0 + WBC
|
Fully adjusted
|
|---|
|
OR
|
[95% CI]
|
OR
|
[95% CI]
|
OR
|
[95% CI]
|
OR
|
[95% CI]
|
|---|
|
Age
|
0.94
|
[0.91; 0.97]
|
0.96
|
[0.92; 0.99]
|
0.95
|
[0.92; 0.98]
|
0.96
|
[0.93; 0.99]
|
|
Sex
|
Men
|
ref
| |
ref
| |
ref
| |
ref
| |
|
Women
|
1.39
|
[0.88; 2.20]
|
1.56
|
[0.96; 2.52]
|
1.41
|
[0.88; 2.25]
|
1.56
|
[0.96; 2.55]
|
|
Patients’ SEP (quintile of deprivation score)
|
Q1 – least
|
ref
| |
ref
| |
ref
| |
ref
| |
|
Q2
|
1.02
|
[0.50; 2.09]
|
0.89
|
[0.42; 1.89]
|
0.94
|
[0.45; 1.98]
|
0.85
|
[0.40; 1.84]
|
|
Q3
|
1.09
|
[0.54; 2.20]
|
1.05
|
[0.50; 2.21]
|
1.07
|
[0.52; 2.19]
|
1.06
|
[0.50; 2.26]
|
|
Q4
|
1.12
|
[0.56; 2.25]
|
1.04
|
[0.51; 2.13]
|
1.04
|
[0.51; 2.12]
|
1.00
|
[0.48; 2.08]
|
|
Q5 – most
|
1.05
|
[0.51; 2.17]
|
1.05
|
[0.50; 2.22]
|
1.06
|
[0.50; 2.24]
|
1.07
|
[0.50; 2.32]
|
|
Charlson comorbidity index
|
0
|
ref
| |
ref
| |
ref
| |
ref
| |
|
1
|
0.42
|
[0.23; 0.75]
|
0.47
|
[0.26; 0.86]
|
0.43
|
[0.23; 0.77]
|
0.47
|
[0.25; 0.86]
|
|
2+
|
0.43
|
[0.23; 0.80]
|
0.51
|
[0.27; 0.98]
|
0.42
|
[0.22; 0.79]
|
0.49
|
[0.25; 0.94]
|
|
Undefinable
|
0.10
|
[0.06; 0.20]
|
0.15
|
[0.07; 0.29]
|
0.12
|
[0.06; 0.22]
|
0.15
|
[0.08; 0.31]
|
|
Performance status
|
0/1
| | |
ref
| | | |
ref
| |
|
2
| | |
0.88
|
[0.46; 1.68]
| | |
0.92
|
[0.48; 1.79]
|
|
3/4
| | |
0.21
|
[0.10; 0.45]
| | |
0.24
|
[0.11; 0.52]
|
|
Undefinable
| | |
0.36
|
[0.20; 0.65]
| | |
0.41
|
[0.22; 0.76]
|
|
White blood cell (WBS) counts (tercile)
|
Tercile 1 – low
| | | | |
ref
| |
ref
| |
|
Tercile 2 – intermediate
| | | | |
0.76
|
[0.44; 1.30]
|
0.85
|
[0.49; 1.49]
|
|
Tercile 3 – high
| | | |
0.41
|
[0.23; 0.72]
|
0.51
|
[0.28; 0.92]
|
|
Undefinable
| | | |
0.13
|
[0.03; 0.71]
|
0.16
|
[0.03; 0.93]
|
- Population is selected among those who were not considered for intensive chemotherapy. Generalized linear model with logit link function, adjusted odds ratios [95% Confidence Intervals]
