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Table 2 Characteristics associated with colorectal cancer mortality post diagnosis and colonoscopy history (deaths by December 31st, 2013, registered in 2003–2013, South Australia (n = 12,906)

From: Pre-diagnostic colonoscopies reduce cancer mortality - results from linked population-based data in South Australia

Characteristics

Colorectal cancer death n = 3771

Other death n = 1621

Alive n = 7514

Unadjusted SHR (95% CI) *

Mean age (SD) at diagnosis (years)

72.2 (13.2)

78.3 (10.0)

67.4 (12.6)

1.13 (1.11–1.16)

Age at diagnosis (years)

  < 60

652 (17.3%)

68 (4.2%)

1887 (25.1%)

1.00

 60–69

781 (20.8%)

193 (11.9%)

2118 (28.2%)

1.00 (0.91–1.11)

 70–79

1056 (28.0%)

495 (30.5%)

2194 (29.2%)

1.13 (1.03–1.25)

  > 80

1280 (34.0%)

865 (53.4%)

1310 (17.5%)

1.70 (1.55–1.87)

Sex

 Male

2014 (53.6%)

917 (56.6%)

3881 (53.6%)

1.00

 Female

1745 (46.4)

703 (43.4%)

3361 (46.4%)

1.03 (0.97–1.10)

Country of birth

 Australia & NZ

2599 (71.1%)

1113 (71.1%)

4980 (68.3%)

1.0

 Europe

957 (26.2%)

427 (27.3%)

1700 (23.3%)

1.03 (0.96–1.11)

 North Africa/ Middle East

10 (0.3%)

2 (0.1%)

22 (0.3%)

0.99 (0.54–1.82)

 Asia and Pacific Islands

47 (1.2%)

15 (1.0%)

106 (1.5%)

0.87 (0.66–1.15)

 Americas

14 (0.4%)

2 (0.1%)

23 (0.3%)

1.35 (0.80–2.28)

 Africa (other)

32 (0.9%)

7 (0.5%)

461 (6.3%)

0.66 (0.46–0.95)

Indigenous

 No

3653 (99.5%)

1576 (99.9%)

6843 (99.7%)

1.00

 Yes

17 (0.5%)

2 (0.1%)

19 (0.3%)

1.85 (1.12–3.05)

Remoteness

 Major city

2663 (70.6%)

1199 (74.0%)

5334 (71.0%)

1.00

 Inner regional

386 (10.2%)

156 (9.6%)

859 (11.4%)

0.95 (0.85–1.05)

 Outer regional and remote

722 (19.2%)

266 (16.4%)

1319 (17.6%)

1.11 (1.02–1.20)

SES disadvantage quintile

 1st (most disadvantage)

1020 (27.1%)

406 (25.1%)

1785 (23.8%)

1.00

 2nd

838 (22.3%)

346 (21.4%)

1687 (22.5%)

0.92 (0.84–1.00)

 3rd

689 (18.3%)

365 (22.5%)

1427 (19.0%)

0.84 (0.77–0.93)

 4th

699 (18.6%)

283 (17.5%)

1442 (19.2%)

0.89 (0.81–0.98)

 5th (least disadvantage)

519 (13.8%)

220 (13.6%)

1165 (15.5%)

0.82 (0.73–0.91)

Local Health Network code

 Country Health SA

1211 (32.1%)

474 (29.2%)

2428 (32.3%)

1.00

 Central Adelaide

1122 (29.8%)

527 (32.5%)

2127 (28.3%)

1.00 (0.92–1.09)

 Northern Adelaide

755 (20.0%)

273 (16.8%)

1472 (19.6%)

1.04 (0.95–1.14)

 Southern Adelaide

683 (18.1%)

347 (21.4%)

1484 (19.8%)

0.90 (0.82–0.98)

Years survived on Dec 31st 2013 Median (IQR)

2.8 (0.9–5.1)

2.8 (0.9–5.1)

4.4 (1.9–7.2)

 

Cancer staging (max spread)

 Local

439 (18.1%)

547 (59.6.%)

2494 (58.2%)

1.00

 Regional

783 (32.2%)

277 (30.2%)

1393 (32.5%)

3.05 (2.72–3.42)

 Distant

1208 (49.7%)

94 (10.2%)

401 (9.4%)

11.41 (10.24–12.71)

Pre-diagnosis colonoscopy

 No

2505 (66.4%)

899 (55.5%)

4790 (63.8%)

1.00

 Yes

1266 (33.6%)

722 (44.5%)

2724 (36.3%)

0.83 (0.78–0.89)

Follow-up time from initial colonoscopy to diagnosis

  < 1 year

883 (69.8%)

529 (73.3%)

1577 (57.9%)

1.00

  > =1 year

383 (30.3%)

193 (26.7%)

1147 (42.1%)

0.82 (0.73–0.93)

Pre-diagnostic colonoscopy examinations

 One

1023 (80.8%)

560 (77.6%)

1991 (73.1%)

1.00

 Two

179 (14.1%)

119 (16.5%)

446 (16.4%)

0.90 (0.77–1.05)

  > = 3

64 (5.1%)

43 (6.0%)

287 (10.5%)

0.63 (0.49–0.81)

  1. *SHR (sub Hazard ratio) from competing risk survival analysis with death other than colorectal cancer as competing risk in the univariate model; cell totals < overall totals due to missing records